Migration und Tuberkulose

Im Jahr 2015 erreichte die Zahl der Migranten weltweit 244 Millionen, die höchste Zahl seit Ende des Zweiten Weltkriegs. Hierunter fallen auch 22 Millionen Geflüchtete. In Deutschland sind Tuberkulosefälle unter den Migranten eine entscheidende Ursache für die gestiegene Zahl an Erkrankten. Prävention, Diagnose und Therapie der Tuberkulose erfordern differenzierte Kenntnisse und Anstrengungen – abhängig von Herkunft und Lebensweg der Betroffenen.

• Literatur

• 1 Robert Koch-Institut. Bericht zur Epidemiologie der Tuberkulose in Deutschland für 2017. Berlin: Robert Koch-Institut; 2018
• 2 Sandgren A, Schepisi MS, Sotgiu G. et al. Tuberculosis transmission between foreign- and native-born populations in the EU/EEA: a systematic review. Eur Respir J 2014; 43: 1159-1171
• 3 Barniol J, Niemann S, Louis VR. et al. Transmission dynamics of pulmonary tuberculosis between autochthonous and immigrant sub-populations. BMC Infect Dis 2009; 9: 197
• 4 World Health Organization. Global Tuberculosis Report 2017. Im Internet: http://www.who.int/tb/publications/global_report/en/ Stand: 07.03.2019
• 5 Bozorgmehr K, Razum O, Saure D. et al. Yield of active screening for tuberculosis among asylum seekers in Germany: a systematic review and meta-analysis. Euro Surveill 2017; 22: pii:30491
• 6 Herzmann C, Golakov M, Malekzada F. et al. Radiological screening of refugees in Germany. Eur Resp J 2017; 49: pii:1602487
• 7 Robert Koch-Institut. Thoraxröntgenuntersuchung bei Asylsuchenden gemäß § 36 Absatz 4 IfSG (05.10.2015). Im Internet: https://www.rki.de/DE/Content/InfAZ/T/Tuberkulose/Tuberkulose_Roentgen-Untersuchungen_Asylsuchende.html Stand: 07.03.2019
• 8 Marx FM, Fiebig L, Hauer B. et al. Higher Rate of Tuberculosis in Second Generation Migrants Compared to Native Residents in a Metropolitan Setting in Western Europe. PLoS One 2015; 10: e0119693
• 9 Kunst H, Burman M, Arnesen TM. et al. Tuberculosis and latent tuberculous infection screening of migrants in Europe: comparative analysis of policies, surveillance systems and results. Int J Tuberc Lung Dis 2017; 21: 840-851
• 10 Heuvelings C, de Vries G, Greve P. et al. Effectiveness of interventions for diagnosis and treatment of tuberculosis in hard-to reach populations in countries of low and medium tuberculosis incidence: a systematic review. Lancet Infect Dis 2017; 17: e144-e158
• 11 Chan I, Kaushik N, Dobler C. Post-migration follow-up of migrants identified to be at increased risk of developing tuberculosis at pre-migration screening: a systematic review and meta-analysis. Lancet Infect Dis 2017; 17: 770-779
• 12 Altice F, Azbel L, Stone J. et al. The perfect storm: incarceration and the high risk environment perpetuating transmission of HIV, hepatitis c virus, and tuberculosis in Eastern Europe and Central Asia. Lancet 2016; 388: 1228-1248
• 13 Pareek M, Greenaway C, Noori T. et al. The impact of migration on tuberculosis epidemiology and control in high-income countries. a review. BMC Med 2016; 14: 48
• 14 Smieja M, Marchetti C, Cook D. et al. Isoniazid for preventing tuberculosis in non-HIV infected persons. Cochrane Database Syst Rev 2000; (02) CD001363
• 15 Akolo C, Adetifa I, Shepperd S. et al. Treatment of latent tuberculosis infection in HIV infected persons. Cochrane Database Syst Rev 2010; (01) CD000171
• 16 World Health Organization (WHO). Guidelines on the management of latent tuberculosis Infection. WHO; 2015: 9789241548908. Im Internet: http://www.who.int/tb/publications/ltbi_document_page/en/ Stand: 07.03.2019
• 17 Diel R, Loddenkemper R. Screening auf Tuberkulose bei Patienten mit Migrationshintergrund. Pneumologe 2017; 14: 165-169
• 18 Pease C, Hutton B, Yazdi F. et al. Efficacy and completion rates of rifapentine and isoniazid (3HP) compared to other treatment regimens for latent tuberculosis infection: a systematic review with network meta-analyses. BMC Infect Dis 2017; 17: 265
• 19 Schaberg T, Bauer T, Brinkmann F. et al. S2k-Leitlinie: Tuberkulose im Erwachsenenalter. Pneumologie 2017; 71: 325-397
• 20 Schönfeld N, Bergmann T, Vesenbeckh S. et al. Minimal inhibitory concentrations of first-line drugs of multidrug-resistant tuberculosis isolates. Lung India 2012; 29: 309-312
• 21 Wahidi M, Herth F, Yasufuku K. et al. Technical Aspects of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: CHEST Guideline and Expert Panel Report. Chest 2016; 149: 816-835
• 22 Loddenkemper R, Schönfeld N. Medical thoracoscopy. Curr Opin Pulm Med 1998; 4: 235-238
• 23 Haddy TB, Rana SR, Castro O. Benign ethnic neutropenia: what is a normal absolute neutrophil count?. J Lab Clin Med 1999; 133: 15-22
• 24 World Health Organization. WHO country profiles. WHO 2018:. Im Internet: http://www.who.int/tb/country/data/profiles/en/ Stand: 07.03.2019
• 25 Otto-Knapp R, Bös L, Schönfeld N. et al. Resistenzen gegen Zweitlinienmedikamente bei Migranten mit multiresistenter Tuberkulose in der Region Berlin. Pneumologie 2014; 68: 496-500
• 26 Walker M, Merker M, Knoblauch M. et al. A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study. Lancet Infect Dis 2018; 18: 431-440
• 27 Tavares AM, Fronteira I, Couto I. et al. HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality. PLoS One 2017; 12: e0185526
• 28 Barrett J, Warrell CE, Macpherson L. et al. The changing aetiology of eosinophilia in migrants and returning travellers in the Hospital for Tropical Diseases, London 2002–2015: An observational study. J Infect 2017; 75: 301-308
• 29 Schmiedel S, Boecken G, Burchard G. et al. AWMF-Leitlinie: Diagnostik und Therapie der Schistosomiasis (Bilharziose). 2017:. Im Internet: http://www.awmf.org/leitlinien/detail/ll/042-005.html Stand: 07.03.2019
• 30 Abbott A. The mental-health crisis among migrants. Nature 2016; 538: 158-160
• 31 Schellong J, Epple F, Weidner K. Psychosomatik und Psychotraumatologie bei Geflüchteten und Migranten. Internist (Berl) 2016; 57: 434-443